New research published in the EMBO Journal suggests that a specific type of neuron in the brain can influence the way the body breaks down and stores nutrients, providing further insight into obesity and other metabolic diseases.
Venture-capital backed Immune Targeting Systems Ltd has reported the results of its first clinical test of a new synthetic peptide vaccine for influenza A. It has also announced changes in top management ahead of a new funding round.
Up to 9,000 small-molecule compounds with potential as future drugs are being made available free of charge to academic researchers around the world by MRC Technology, the technology transfer arm of the UK’s Medical Research Council.
UCB SA has signalled its commitment to biologic drugs with the construction of a new manufacturing plant in Belgium that will produce cell culture-based therapeutic proteins. The plant will supply product for UCB research and trials.
Sweden has announced plans to invest $320 million over four years in the life sciences of which one third will support new infrastructure for projects in translational medicine. The investment will be concentrated in the Stockholm-Uppsala region.
GlaxoSmithKline Plc has invested $5.5 million in Response Genetics Inc through a private share placement giving it 15.2% of the expanded share capital of the US diagnostics company. GSK in-licenses genetic testing services from the company.
The Anglo/Russian pharmaceutical company, Pro Bono Bio Group Plc, has reported promising pre-clinical data for a new group of haemophilia products that would act longer than existing blood factor proteins thereby enabling patients to self-administer treatments at home. The preclinical data still must be confirmed in human trials and approved by a regulator before any products could be marketed.
AstraZeneca Plc and the Broad Institute in Cambridge, Massachusetts, US have announced a collaboration to identify new chemical compounds targeting bacterial and viral infections. Financial details were not disclosed.
SV Life Sciences and Novo A/S are among the four new investors supporting a Series B financing round for Karus Therapeutics Ltd of the UK. The investors have thus far committed $7.6 million to support programmes in inflammation and cancer.
Eli Lilly and Company said that a Phase 3 trial (Pointbreak) of a combination treatment for patients with nonsquamous non-small cell lung cancer has failed to meet its primary endpoint of improved overall survival.