MorphoSys AG has received grant funding for up to €1 million from the German Federal Ministry of Education and Research to support development of antibodies against two undisclosed G protein-coupled receptors (GPCRs) . The two-year grant will cover the cost of early drug development.
A Phase 3 study of a new drug regime for tuberculosis, which involved replacing the antibiotic moxifloxacin for one of two other drugs, failed to shorten the treatment time for the disease from six to four months. But the new regime was safe, according to the Global Alliance for TB Drug Development.
Nicox SA has continued its expansion into ophthalmology with agreements to acquire the French eye-care company Laboratoires Doliage and a development-stage asset for viral conjunctivitis from Marinomed Biotechnologie GmbH of Austria.
Real world data from an experimental vaccine for birch pollen allergy, AllerT, have shown statistically significant reductions in seasonal allergy symptoms, as well as an effect into a second pollen season, according to the developer, Anergis SA.
Merck KGaA of Germany has decided to discontinue the clinical development of the immunotherapy tecemotide in non-small cell lung cancer following the failure of a Japanese study to show effectiveness on any trial endpoint.
Eli Lilly and Company said the results of a Phase 3 study of its antibody treatment Cyramza (ramucirumab), which has already been approved for advanced gastric cancer, met its primary endpoint of overall survival in patients with metastatic colorectal cancer.
Data from two Phase 3 studies of the antibody mepolizumab in severe asthma have shown statistically significant reductions in asthma exacerbations and a reduction in the need for daily oral corticosteroid use, according to the developer, GlaxoSmithKline Plc.
Shares of Affimed Therapeutics AG of Germany began trading on the Nasdaq over-the-counter market in the US on 12 September following an initial public offering of eight million new shares. Priced at $7 per share, the shares were trading at $5.98 on 15 September.
AM-Pharma BV of the Netherlands has raised €12.2 million for the further clinical development of its recombinant human alkaline phosphatase product for acute kidney injury and ulcerative colitis – its second major fundraising in three years
Alizé Pharma SAS has raised €5 million to finance further development of an analog of a metabolic hormone that has the potential to treat type-2 diabetes and a rare children’s disease called the Prader-Willi syndrome.