Adaptimmune Ltd, which is developing a T cell therapies for cancer and infectious disease, has raised $104 million in a Series A financing round to support its ongoing work in multiple cancer indications. The oversubscribed round was led by New Enterprise Associates of the US.
Probiodrug AG, a German specialist in Alzheimer’s disease, is planning to make an initial public offering of its shares on the Amsterdam Euronext exchange to support development of a drug that targets small amyloid-beta aggregates.
A candidate treatment for patients with glaucoma, Vesneo, has reached its primary endpoint in a Phase 3 development programme, showing that it can effectively lower intraocular pressure, according to Nicox SA, the developer.
Shire Plc said that it has reached agreement with the US government to pay $56.5 million in fines to settle a civil investigation relating to its sales and marketing practices for three medicines for attention deficit hyperactivity disorder and two for ulcerative colitis.
Regeneron Pharmaceuticals Inc is to appeal against a decision of the European Patent Office (EPO) to revoke its patent for transgenic mouse technology, a patent that was successfully challenged by Kymab Ltd of the UK.
Merck KGaA has become the second large German pharmaceutical company to reconfigure its profile with the acquisition of Sigma-Aldrich Co for $17 billion. The deal, announced on 22 September, has been approved by the boards of both companies.
CureVac GmbH, a pioneer in RNA technology, is set to work with Boehringer Ingelheim on two new oncology projects that will seek to improve outcomes for patients with non-small lung cancer by leveraging existing treatments with a cancer vaccine.
Kymab Ltd has successfully challenged a European patent issued to its competitor, Regeneron Pharmaceuticals Inc, for transgenic mouse technology that is a foundation for developing therapeutic antibodies. The patent was said to lack an inventive step as required by European patent law.
A court in Hunan Province, China has found GlaxoSmithKline’s subsidiary, GSK China Investment Co Ltd (GSKCI), guilty of bribing non-government personnel and ordered it to pay a fine of £297 million, the UK company announced on 19 September.
Evotec AG is to take legal action against Andromeda Biotech Ltd following allegations that certain employees of the Israel-based company had engaged in misconduct in relation to a Type 1 diabetes programme for which Evotec was due milestone payments and royalties.