ImevaX GmbH, a 2014 spin-out of the Technische Universität Mϋnchen (TUM) in Germany, has completed a €7.5 million Series A financing round to advance a candidate vaccine against Helicobacter pylori, a major cause of stomach ulcers.
Advent Life Sciences, which is part of Advent Venture Partners LLP, has raised £145.5 million for a second fund to seed and build life science companies in the UK, continental Europe and the US. The partnership said the amount raised exceeded its target.
Novartis International AG has reached agreement to sell its influenza vaccines business to CSL Ltd of Australia for US $275 million, subject to regulatory approvals. The transaction is expected to close in the second half of 2015.
Erytech Pharma SA, which publically offered its shares for the first time in April 2013, has returned to the Paris Euronext exchange for €30 million in an offering that was 68% subscribed by US institutions.
Probiodrug AG, a German specialist in Alzheimer’s disease, has raised €22.5 million with an initial public offering of its shares on the Amsterdam Euronext exchange. The offering of 1,524,205 shares was priced at €15.25 per share. Kempen & Co acted as the bookrunner.
Bavarian Nordic A/S, which for years has supplied the US government with smallpox vaccine for its emergency stockpile, has secured a major new deal with Johnson & Johnson Inc to develop a vaccine against the Ebola and Marburg viruses and explore additional disease targets.
DBV Technologies SA, which is developing a patch for peanut allergies, has raised about €104.5 million in an international share offering most of which was in American depositary shares on Nasdaq in the US.
Forendo Pharma OY of Finland has secured €12 million from a syndicate of investors including Novartis Venture Fund and MS Ventures to bring a candidate drug for endometriosis into the clinic. The drug inhibits the enzyme 17-beta-hydroxysteroid dehydrogenase 1.
Shire Plc said that it has agreed with AbbVie Inc to end their proposed merger, and that a break fee of $1.635 billion is now payable to it. The Dublin, Ireland-based company said it was well positioned to continue as an independent business.
Bicycle Therapeutics of the UK has raised £20 million in equity financing to bring its candidate peptide therapeutics into clinical development in cancer indications. The technology combines features of both antibodies and small-molecule drugs.