Switzerland-based Anergis SA has raised CHF 14.5 million (€12.1 million) from European and US-based investors in order to progress its lead vaccine against birch pollen allergy into a Phase 3 study. The vaccine consists of synthetic long peptides.
Evgen Pharma Plc, which is developing cancer and neurology products based on a naturally occurring chemical, has announced its intention to make an initial public offering of up to £20 million worth of its shares on the AIM market of the London Stock Exchange in mid-December.
BTG Plc is to pay up to $475 million to acquire privately-held PneumRx Inc of California which has a medical device approved in Europe to treat emphysema. The purchase price consists of an upfront payment of $230 million and up to $245 million in milestones.
Sanofi SA and Evotec AG are in negotiations for a collaboration under which Evotec would assume much of Sanofi’s drug discovery operations, including the management of the French company's global screening compound library in Toulouse.
Switzerland-based GeNeuro SA and Les Laboratoires Servier SAS of France have formed a partnership to develop an antibody that targets a protein expressed in the brain lesions of patients with multiple sclerosis thereby addressing a causal factor of the disease.
Ascendis Pharma A/S, a Denmark-based specialty pharmaceutical company with new prodrug technology, has raised $60 million from a syndicate co-led by US-based Sofinnova Ventures.
BioMarin Pharmaceutical Inc of California has made an agreed bid to buy Prosensa Holding NV of the Netherlands for $680 million in cash.
London-based Cell Medica Ltd has raised £50 million from institutional investors to support development of its lead oncology product, CMD-003, for the treatment of patients with advanced lymphomas associated with the Epstein Barr virus.
Pfizer Inc has signalled its determination to stay ahead in oncology by agreeing to pay Merck KGaA up to $2.85 billion for rights to the German company’s early-stage checkpoint inhibitor and collaborate on up to 20 other immuno-oncology programmes.
Dendreon Corporation, developer of the first ever FDA-approved cellular immunotherapy, announced on 10 November that it had filed for protection from its creditors under Chapter 11 of the US Bankruptcy Code.