Ryboquin Ltd, a virtual Scottish company with no salaried employees, has raised £1.3 million for the scaling up production of its lead product, Ryboquin ECP-102, which boosts the effectiveness of chemotherapy in cancer patients.
Nouscom SA, a new developer of cancer vaccines raised €12 million in a Series A financing round earlier this month to support the development of a portfolio of products based on oncolytic viruses and viral vectors. The company is based in Basel, Switzerland.
The European Medicines Agency has launched a review of guidelines for the testing of new medicines in volunteers following the death of one person and the hospitalisation of five others in France in January. The case is the most serious incident to come to light since 2006 when an experimental immunotherapy seriously injured six volunteers in a first-in-human study the UK.
The European Medicines Agency has given positive opinions to two new combination drugs to treat chronic hepatitis C virus (HCV) infection, both of which directly target proteins that cause the virus to replicate in humans.
AstraZeneca Plc has received a complete response letter (CRL) from the US Food and Drug Administration rejecting its application to market a new drug for hyperkalaemia called ZS-9. The CRL relates to an unspecified manufacturing issue.
Aleva Neurotherapeutics SA, a Swiss company with a candidate device for deep brain stimulation, has obtained $18 million in Series C financing enabling it to prepare for the registration of its product in Europe in 2017.
The shareholders of Shire Plc have voted to approve management’s proposed merger with Baxalta Inc to create a global company focused on developing drugs for rare diseases and other specialised conditions. The $32 billion deal comprises cash and shares.
A study published by investigators at the Massachusetts General Hospital (MGH) and Harvard University suggests that the blood-brain barrier in humans weakens with age and that the build-up of amyloid-beta plaques associated with Alzheimer’s disease is a response to the threat of pathogens coming through the barrier.
Angle Plc, a specialist medical technology company listed on the AIM market in London, has placed about 15.8 million new shares with institutional investors raising £10.2 million in order to commercialise a liquid biopsy test for cancer based on the detection of circulating tumour cells.
Sanofi SA has filed papers with the US Securities and Exchange Commission (SEC) in an effort to remove and replace the board of Medivation Inc following that company’s rejection in late April of the French company’s unsolicited $9.3 billion takeover bid.