Regenerative Medicine

TiGenix reports first half loss; plans to increase working capital

Country
Belgium

TiGenix NV, the Belgian developer of cell therapies, reported a 7.5% increase in sales to €2.3 million in the first half as it continued to roll out the cell therapy, ChondroCelect. In response to an auditor's note, it announced plans to raise working capital.

New role of endothelial precursor cells?

Country
United States

Results from an animal study suggest that endothelial precursor cells could play a role in minimising initial brain injury from a stroke and help repair stroke damage, according to an article in the August issue of STEM CELLS Translational Medicine.

KU Leuven gains rights to gene technology

Country
Belgium

The Belgian university, KU Leuven, has joined forces with a small company in Finland to develop new immunotherapies using a proprietary gene expression technology. The Finnish partner is FIT Biotech of Tampere.

Cellular Dynamics prices IPO

Country
United States

Cellular Dynamics International Inc, which is a producer of induced pluripotent stem cells (iPSCs), has priced its previously-announced initial public offering of shares at $12 per share. The shares will begin trading today on Nasdaq.

ReNeuron secures new funding

Country
United Kingdom

The ReNeuron Group Plc has secured new funding commitments of £33 million, enabling it to advance its three allogeneic stem cell programmes through Phase 2 development. The funding includes a large grant from the Welsh government.

TiGenix raises €6.5 million in share placement

Country
Belgium

TiGenix NV has raised €6.5 million in a private placement of its shares to finance the continued roll-out of its cell therapy for knee injuries ChondroCelect. A total of 26 million new shares were placed via an accelerated bookbuilding procedure.

RNA viral vector used to generate iPS cells

Country
United States

Using an RNA viral vector, researchers from the University of California, San Francisco have created induced pluripotent stem cells (iPSC) from blood cells which they say can be easily differentiated into haematopoietic stem and progenitor cells.

Synthetic transcription factors used to create iPS cells

Country
United Kingdom

Scientists from the UK and China have created induced pluripotent stem (iPS) cells from adult cells using synthetic transcription factors created in the laboratory. They claim the method is safer and more accurate than other means of creating iPSCs.

New approach to organ regeneration

Country
Japan

Japanese researchers have shown that it is possible to create a vascularised and functional human liver from human induced pluripotent stem cells – a finding that has implications both for organ regeneration and the testing of new drugs for toxicity.

Cardio3 BioSciences prices IPO

Country
Belgium

Cardio3 BioSciences SA of Belgium said that its previously announced initial public offering of shares will commence on 21 June and end on 3 July. The indicative price range of the shares is between €16.65 per share and €19.00 per share.