ReNeuron Plc has reported positive data from a Phase 2 trial of its allogeneic cell therapy for patients disabled by a stroke and plans to apply to regulatory authorities in the US and Europe to begin a pivotal study that could lead to possible registration.
The cell-therapy company TiGenix NV has announced plans to make an initial public offering of its shares on the Nasdaq exchange in the US in order to raise money for the clinical development of its portfolio. The company is already listed on Euronext Brussels.
Spark Therapeutics Inc has agreed to make a $10 million cash payment plus an equity investment in Selecta Biosciences Inc for access to a nanoparticle technology that could be used to modulate the immune system and allow repeat dosing of a gene therapy.
Regulators in both the US and Europe are preparing for the first submissions of a new class of cancer drugs that have been shown to vanquish cancer in some patients b
Cell Medica Ltd has expanded an existing partnership with the Baylor College of Medicine in Texas, US to develop allogeneic cell therapies based on engineered immune cells generated from healthy donors. The cells are invariant natural killer T (NKT) cells.
If the cell therapy industry were a housing project, then arguably it would be at the construction stage – deciding what materials are needed to make a safe and durable product. Manufacture is a key issue for the industry, but one that is just now being confronted, according to participants at a meeting of the Alliance for Regenerative Medicine that took place in London on 3 November.
The Phacilitate conference on cell and gene therapy in Berlin on 21 to 22 September produced more uplifting statistics about how the new regenerative technologies are enabling patients with refractory disease to gain a new lease on life.
Amgen Inc has signed a research agreement with two Milan-based institutions to develop an ex-vivo gene therapy for cancer. The research will be based on some of the same principles that guided the development of Strimvelis, an ex vivo stem cell gene therapy that was approved by the European Commission in May of this year.
Cell Medica Ltd has strengthened its hand in the field of T cell therapy with a new collaboration around T cell receptor technology. Having recently expanded a partnership with Baylor College of Medicine in Texas, US, and acquired the Delenex Therapeutics AG antibody company in Switzerland, the company has now entered into a partnership with University College London (UCL) to develop genetically engineered T cell receptor products for cancer.