Atlas Ventures of the US has entered into new partnership agreements with Amgen and Novartis in connection with the closing of its ninth investment fund Atlas IX. The two companies are limited partners of the fund, and will participate in the creation of new startup companies.
AbbVie Inc (formerly part of Abbott Laboratories) is expanding its collaboration with Galápagos NV of Belgium to take the Galápagos JAK1 inhibitor, GLPG0634, into Crohn’s disease. The molecule is already being investigated for rheumatoid arthritis.
Cardio3 BioSciences SA, which has an autologous cell therapy for patients with chronic heart failure in the clinic, has raised €19 million in a private placement with existing investors to finance the clinical development of its lead product.
Symphogen A/S of Denmark has raised an additional €41 million from private investors towards the development of its portfolio of compounds in oncology which are antibody mixture products addressing multiple targets in a single product.
Oxford BioMedica Plc has signed a contract with Novartis to supply the Swiss company with lentiviral vector material for clinical trials involving a new immunotherapy. The contract is valued at up to £4 million.
In another example of Big Pharma collaboration in the area of diabetes, Merck & Co Inc has announced plans to collaborate with Pfizer in the development and commercialisation of ertugliflozin, a Phase 3-ready diabetes drug in the SGLT2 class.
GlaxoSmithKline Plc has ended a collaboration with Impax Pharmaceuticals on a late-stage Parkinson’s disease drug, citing delays in the drug’s anticipated regulatory review and launch dates in countries where GSK has commercialisation rights.
Galápagos NV has raised €53.9 million in a private placement of its shares to institutional investors in the US and Europe. The proceeds will be used to fund its internal pipeline as well as to enable possible in-licensing deals.
A therapeutic vaccine for human papillomavirus (HPV) that is being developed by Genticel SA of France has received backing by a syndicate led by Wellington Partners, raising €18.2 million in new capital.
The German molecular diagnostics company, Curetis AG, has raised €12.5 million in a Series B round to further test and commercialise its technology for detecting antibiotic resistant bacteria. The round was led by HBM Partners of Switzerland.