Heptares Therapeutics Ltd is set to receive an undisclosed milestone from MorphoSys AG for delivering a stabilised form of a G protein-coupled receptor (GPCR) against a target selected by the German company. This is the first step towards developing antibodies targeting the protein complex.
The market for initial public offerings for biotechnology companies in the US is likely to remain open for some time as investors position themselves to take advantage of the demand for new medical therapies.
Hutchison MediPharma Ltd (HMP), the R&D unit of Hutchison China MediTech Ltd, has secured a licensing agreement for an early-stage oncology compound with Eli Lilly and Company – its third deal for a molecule in its six-compound clinical portfolio. The deal was announced on 9 October.
The Dutch biotech company, Pharming Group NV, has raised €12 million in a private share placement, sweetened with warrants, with existing and new institutional investors. The proceeds will support the manufacture of Ruconest, which is awaiting FDA approval.
The German vaccine developer CureVac GmbH has secured a licensing agreement with Janssen Pharmaceuticals (Johnson & Johnson Inc) to develop an influenza vaccine based on its messenger RNA technology. Financial terms were not disclosed.
Pharmalink AB, a Sweden-based specialty pharmaceutical company, has raised SEK96 million (€11.1 million) in a Series C round to advance the clinical development of products to treat patients with cancer and renal disease.
The fortunes of biotech, at least in the US, have shifted. Gone is the gloom and in its place has arrived something close to euphoria, driven by a wave of initial public offerings (IPOs).
Ablynx NV and Merck Serono have expanded a partnership dating from 2008 to focus on early discovery across a range of therapeutic areas with the goal of identifying antibody-derived therapeutic proteins for later stage development.
Galapagos NV and AbbVie Inc have reached an agreement to co-develop small molecule drugs to treat cystic fibrosis. The goal is to identify compounds that can correct defects and/or restore the activity to the cystic fibrosis transmembrane regulator protein.
Ablynx NV has secured a licensing deal with AbbVie Inc for its antibody-derived therapeutic protein ALX-0061 to treat inflammatory diseases. The product targets the interleukin-6 receptor and is in Phase 2 for rheumatoid arthritis and systemic lupus erythematosus (SLE).