Sphere Fluidics Ltd of the UK, which has developed technology to analyse single cells, has raised $2.5 million in a Series A round from a syndicate led by 24Haymarket of London. The company’s technology comes from the chemistry department of Cambridge University.
4SC AG has expanded its collaboration with BioNTech AG with the signing of a research agreement to discover new compounds against cancer. The three-year agreement is being executed through 4SC’s wholly-owned research unit 4SC Discovery GmbH.
The US regulatory review of Zealand Pharma A/S’s new drug for Type 2 diabetes, lixisenatide, is set to begin following the Food and Drug Administration’s acceptance of a registration file from the company’s partner, Sanofi SA. Lixisenatide is a GLP-1 receptor agonist.
The US Food and Drug Administration has approved a second indication for the Novartis immunosuppressant everolimus: to prevent organ rejection in adult liver transplant patients. The same indication was approved in Europe in late 2012.
Clavis Pharma ASA expects to report top-line Phase 3 results for its compound for acute myeloid leukaemia (AML) by the end of the first quarter. The compound, elacytarabine, is a derivative of cytarabine- the licensed AML chemotherapy.
The US Food and Drug Administration has granted priority review status to the prospective HIV/AIDS medicine, dolutegravir, which has been developed by ViiV Healthcare, a business venture among GSK, Pfizer Inc and Shionogi & Co.
With a new chief executive set to take charge this spring, Shire Plc has settled two outstanding lawsuits and started to broaden its specialist medicines portfolio. Flemming Ørnskov of Bayer AG will take over as CEO on 30 April, succeeding Angus Russell, who is retiring.
Ablynx NV has reported further efficacy data for its early-stage rheumatoid arthritis drug ALX-0061 which showed that up to 75% of patients achieved remission as defined by the DAS28 measure of disease activity at week 24 in a Phase 2 study.
The US Food and Drug Administration has granted ‘priority review’ status to the Algeta ASA investigational therapy for the treatment of castration-resistant prostate cancer patients with bone metastases. The product (radium-223) is an alpha-emitting nuclide.
MorphoSys AG and Heptares Therapeutics Ltd have entered into a collaboration to generate candidate antibody therapeutics targeting G protein-coupled receptors (GPCRs). The disease targets will be proposed by MorphoSys.