Company News

Therapeutic vaccine producer raises €13.1 million

Location

France

A French producer of therapeutic vaccines for cancer has raised €13.1 million from private and public sources in order to bring its lead product, a therapeutic human papillomavirus vaccine, into the clinic.

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Ark Therapeutics drops Cerepro appeal

Location

United Kingdom

Ark Therapeutics Group Plc has dropped its appeal against a negative opinion from the European Medicines Agency for its gene therapy for brain cancer, Cerepro. It also announced that it is in talks about a possible takeover of the company. Ark disclosed the developments on 9 March 2010.

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Zalutumumab fails to meet primary endpoint of overall survival

Location

Denmark

Genmab A/S said that its antibody for head and neck cancer, zalutumumab, has failed to show overall survival in a Phase 3 study in which the drug was being tested in combination with best supportive care versus best standard care alone.

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Recentin fails to meet primary endpoint in cancer trial

Location

United Kingdom

AstraZeneca Plc said that its candidate drug, Recentin (cediranib), for patients with first-line metastatic colorectal cancer, failed to meet its primary endpoint of non-inferiority in progression-free survival in a Phase 2/3 trial.

 

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Roche and Biogen Idec suspend RA trials with ocrelizumab

Location

Switzerland

The Roche Group and Biogen Idec of the US have suspended clinical trials of the humanized anti-CD20 monoclonal antibody, ocrelizumab, in four rheumatoid arthritis trials because of safety issues. The drug was in Phase 2 and 3 trials.

 

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Key milestones for BioAlliance in the second quarter

Location

France

BioAlliance Pharma SA is looking ahead to three possibly transforming events in the second quarter of 2010 that could secure its standing as a recognised specialty pharmaceutical company in Europe.

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Alzheimer’s drug fails at Phase 3

Location

United States

An investigational drug for patients with Alzheimer’s disease, Dimebon (latrepirdine), has failed in a Phase 3 trial because it could not show statistically significant improvements in patients compared with placebo for cognition and global function.

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Intercell expects data in 2010 on vaccines against hospital-acquired infections

Location

Austria

Intercell AG expects to report data in 2010 on two late-stage vaccine candidates against hospital-acquired infections, conditions that have become serious in recent years because of bacterial resistance to marketed antibiotics.

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Merck to acquire Millipore for $7.2 billion

Location

Germany

Merck KGaA of Germany has made an agreed bid for the US service provider, Millipore Corp, in a transaction valued at $7.2 billion, including net debt. The merged company is expected to have critical mass in bioresearch and bioprocessing.

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Ablynx sees clinical progress in 2010

Location

Belgium

Ablynx NV expects that its heavy-chain-only antibody technology will show clinical progress in 2010 from its own and partnered programmes. It also expects to report progress on new delivery technologies.

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