Company News

Gates Foundation funds Novartis drug

The Bill & Melinda Gates Foundation is to provide $6.5 million to Novartis to support development of a preclinical compound that has potential to treat cryptosporidiosis, the second leading cause of infectious diarrhoea in children under two years of age.

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Location

Switzerland

FDA approves cancer drug using novel endpoint

The US Food and Drug Administration has used a novel endpoint to approve a new drug for prostate cancer. Measuring metastasis-free survival, the agency decided that the Janssen Pharmaceutical drug Erleada (apalutamide) is effective.

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Location

United States

Pieris raises $44 million in US IPO

An initial public share offering in the US for Pieris Pharmaceuticals Inc has been priced at $8 per share and is expected to raise $44 million. The Nasdaq IPO will enable the company, a developer of protein therapeutics, to advance its bispecific drug candidate targeting the tumour microenvironment.

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Location

United States

Synpromics works with UCL

Synpromics Ltd is bringing its technology for creating synthetic promoters into a partnership with a unit of University College London (UCL) in order to help researchers there develop gene therapies for blood-based disorders. The agreement was announced on 25 January.

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Location

United Kingdom

Cognitive diseases targeted

A new Belgian company has been launched to develop therapies for cognitive disorders using intellectual property from UCB SA. The company has received Series A financing of €17 million from a syndicate of Belgian and international investors.

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Location

Belgium

Novo Nordisk targets obesity

Novo Nordisk A/S, a global producer of diabetes products, reported little change in its sales and a 1% increase in operating profit in 2017 at respectively DKK 112 billion (€15.05 billion) and DKK 49 billion.

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Location

Denmark

ViiV Healthcare sues Gilead over patent

ViiV Healthcare Ltd, the specialist HIV company majority-owned by GlaxoSmithKline Plc, has filed a patent infringement suit against Gilead Sciences Inc over bictegravir, an integrase inhibitor that is part of a combination therapy approved in the US on 7 February.

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Location

United Kingdom

Combination has impact in kidney cancer

An experimental cancer therapy that combines the Roche checkpoint antibody Tecentriq (atezolizumab) and Avastin (bevacizumab) met its co-primary endpoint of progression-free survival in a Phase 3 trial of patients with metastatic renal cell carcinoma.

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Location

Switzerland

Sanofi sees renewed growth

Sanofi SA is forecasting a rise in adjusted earnings per share in 2018 of between 2% and 5% as new products gradually overtake the decline in sales of its core diabetes franchise.

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Location

France

Sales broadly higher at GSK

Sales increased across GlaxoSmithKline’s three business groups in 2017, but the company expressed caution for the year ahead owing to uncertainty about the timing of the market entry of a generic competitor for its respiratory medicine Advair.

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Location

United Kingdom

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