Evotec AG has made a €15 million equity investment in Exscientia Ltd which is developing artificial intelligence technologies to aid drug discovery. The German company already has a research collaboration with Exscientia dating from 2016.
UK-based Autolus Ltd has secured $80 million in Series C capital from new and existing investors to advance the development of its engineered T cell therapies for cancer. The new investors include US-based Cormorant Asset Management and Nextech Invest of Switzerland.
The Bill & Melinda Gates Foundation is to invest up to $40 million in Immunocore Ltd to support the development of the company’s T cell receptor technology (TCR) for infectious disease. The UK company already has partnerships exploring TCRs against cancer.
New longer-term data from a Phase 3 trial of the drug guselkumab for plaque psoriasis has shown that patients achieved consistent rates of skin clearance following treatment at both 52 and 100 weeks, according to the developer Janssen Research & Development LLC.
The European Medicines Agency has recommended two new cancer drugs for approval in Europe, each with an entirely different mechanisms of action. The first is a PARP inhibitor for ovarian cancer and the second, a photodynamic therapy for prostate cancer.
The Italian gene therapy company, Genenta Science srl, has raised €7 million in a Series B financing round to support development of a second tumor indication for its technology platform in addition to multiple myeloma. The funding was announced on 13 September.
Novo Nordisk A/S has reached an agreement with the US government and several states to pay $58.65 million to settle claims of mis-communication over the risks of Victoza, its glucagon-like peptide-1 (GLP-1) drug for Type 2 diabetes. The settlement was announced on 5 September.
A Phase 3 trial of the Bavarian Nordic A/S candidate vaccine for prostate cancer, Prostvac, has been declared futile based on the results of a preplanned interim analysis. The trial’s independent data monitoring committee is recommending the study be discontinued.
Kåre Schultz is set to move to Israel to take the top job at Teva Pharmaceutical Industries Ltd at a time of strategic uncertainty for the generic pharmaceuticals producer. Mr Schultz will be leaving H. Lundbeck A/S in Denmark where he has been chief executive since 2015.
Merck & Co Inc is to acquire Rigontec GmbH of Germany in order to strengthen its portfolio of immuno-oncology compounds led by pembrolizumab. Rigontec has assets that target the retinoic acid-inducible gene I (RIG-I) pathway, part of the innate immune system.