Venture-capital backed Bicycle Therapeutics Ltd has secured Astellas Venture Management as a new investor as part of a tranched equity financing that will bring it £3.75 million in new money to support a move from research into drug discovery.
Two out of the three patients with chronic lymphoid leukaemia (CLL) who were treated with a novel immunotherapy in 2010 remain healthy and in full remission more than two years after treatment, according to University of Pennsylvania researchers.
Genome-based drug discovery received a lift on Monday with the announcement that Amgen Inc has agreed to pay $415 million in cash for DeCODE Genetics of Iceland, long considered to be a leader in population-based studies of human disease.
Sanofi SA has reported data from a Phase 2 trial of a Janus Kinase 2 (JAK2) inhibitor in myelofibrosis which showed the therapy achieved reductions in spleen size and other disease symptoms in 31 randomised patients.
Another potential therapy for patients with melanoma has emerged with the disclosure on 6 December of preliminary results of a therapeutic cancer vaccine in which four patients showed an immune response. The vaccine has been developed by Scancell Holdings Plc.
The Roche Group is to coordinate a new project under the Innovative Medicines Initiative (IMI) under which 1,500 induced pluripotent stem (iPS) cell lines will be generated and characterised for use in the study of disease.
The management of Newron Pharmaceuticals S.p.A has overcome the opposition of a key shareholder and reached an agreement to acquire privately-held NeuroNova AB of Sweden in an all-share deal valued at €15.5 million.
Wilex AG has announced plans to reduce its Munich, Germany workforce by about 25% following the failure of its lead cancer product – an antibody for renal cell carcinoma – to meet its primary endpoint in a Phase 3 trial.
Is it possible to envisage a situation where drugs could be approved sooner by a regulatory authority, but for a more restricted use? And if so, would this be a way for pharmaceutical companies to get real-life data on a drug that could then be used to expand the approved indication and satisfy the requirements of a European health authority for reimbursement?
Smith & Nephew Plc of the UK has moved to strengthen its position in wound care with the acquisition for $782 million in cash of most of the assets of privately-held Healthpoint Biotherapeutics of Fort Worth, Texas, US. The acquisition was announced on 28 November 2012.