The third quarter results from Shire Plc form a basis for expecting that sales of new products could offset much of the anticipated loss of revenue for its best-selling drug, Adderall XR, which goes off-patent in 2009.
A long-standing collaboration among Cellartis AB, the Hagedorn Research Institute of Novo Nordisk, and Professor Henrik Semb of Lund University into diabetes has been upgraded with a view to developing a new cell therapy for the treatment of type 1 diabetes.
Apitope International NV, a biopharmaceutical company based in Belgium, has raised €10 million in a series A financing to develop a peptide therapeutic for multiple sclerosis.
The European Medicines Agency is recommending new marketing authorisations for three proprietary medicinal products, one of which was cleared following an appeal. The EMEA’s recommendations are usually endorsed by the European Commission, which has the power to issue authorisations.
GlaxoSmithKline Biologicals SA has agreed to pay €22.5 million upfront for access to a new vaccine technology developed by AFFiRiS GmbH of Austria. The candidate vaccines are designed to treat Alzheimer’s disease by targeting beta-amyloid, a protein which is understood to be the main constituent of amyloid plaques in the brains of Alzheimer’s disease patients.
Sanofi-Aventis has been told by the European Medicines Agency that patients taking its obesity treatment, Acomplia (rimonabant), are at risk of depression. The agency is therefore recommending the drug be pulled from the European market.
The University of Cambridge is highlighting the results of a Phase 2 study of the monoclonal antibody alemtuzumab which, it says, shows the drug has promise for treating people with multiple sclerosis.
GlaxoSmithKline is facing continued pressure to renew its pharmaceutical-product pipeline. Patents are expiring on several lead compounds opening up competition from the manufacturers of generic medicines
Actelion AG, the Swiss biopharmaceutical company, reported higher third quarter sales and earnings largely as a result of expanding sales of Tracleer (bosentan), its treatment for pulmonary arterial hypertension (PAH).
The Roche Group said that its pharmaceutical research and development pipeline consisted of 65 new molecular entities and 54 additional indications at the end of the 2008 third quarter. Since the start of the year, 10 major projects have entered Phase 3. Roche gave the R&D update on 21 October with the release of its earnings for the first nine months of the year.