Roche Holding AG and its US partner, ImmunoGen Inc, said that interim results from a Phase 2 study of their antibody-drug conjugate, trastuzumab-DM1, showed a better response rate in women with metastatic breast cancer, than with a comparator.
At the request of the US Food and Drug Administration, Abbott Laboratories Inc has agreed to withdraw its obesity drug, Meridia (sibutramine), from the US market because of clinical trial data indicating an increased cardiovascular risk.
MorphoSys AG has reached out to synthetic biology in order to retain a lead in the fast-moving therapeutic antibody business.
Boehringer Ingelheim has decided to discontinue development of flibanserin, its compound for hypoactive sexual desire disorder in pre-menopausal women, following its rejection by the US Food and Drug Administration.
The board of directors of Genzyme Corp has rejected Sanofi-Aventis’s unsolicited bid for the company at $69 per share saying that it undervalues the company and its late-stage pipeline which includes a promising new product for multiple sclerosis.
Novartis International AG is teaming up with a newly-created US company to investigate a method for producing influenza vaccines using synthetic biology and genome sequencing. The technology is being called ‘synthetic genomics.’
The Netherlands-based gene therapy company, Amsterdam Molecular Therapeutics Holding NV (AMT), has raised a gross €14.3 million from a private placement of its shares with investors in order to support its gene therapy portfolio.
DiaGenic ASA of Norway has raised NOK 70 million (€8.7 million) in a private placement of its shares to existing and new investors in order to advance its portfolio of diagnostics. The placement was subscribed approximately 1.4 times.
The Roche Group has paid $175 million for full rights to danoprevir, a candidate protease inhibitor against hepatitis C, which it has been co-developing with InterMune Inc of Brisbane, California since 2006.
IS Pharma Plc, a UK a speciality pharmaceutical company with a turnover £14.2 million in the latest fiscal year, has raised £3.6 million through the issue of new shares to Abingworth LLP. Following the issue, Abingworth will own 13% of the company, The deal was announced on 6 October 2010.