News

Ark Therapeutics continues business refocus

Country
United Kingdom

UK-listed Ark Therapeutics Plc has reported revenue of £0.4 million for the first half of 2011, unchanged from a year as it shifted its business strategy to bio-manufacturing and early-stage research and sold its wound-care business.

Venture capitalists back new UK ophthalmology company

Country
United Kingdom

Novo A/S and SV Life Sciences have committed £8 million in a Series A round to a new UK ophthalmology company that has a portfolio of preclinical assets which are expected to be developed for diabetic macular edema.

GSK spins out technology for hearing disorders

Country
United Kingdom

GlaxoSmithKline Plc has spun out technology for the treatment of hearing disorders into a new company called Autifony Therapeutics Ltd. The company is receiving £10 million in Series A funding from Imperial Innovations and SV Life Sciences.

FDA approves antibody-drug conjugate

Country
United States

The US Food and Drug Administration has approved an antibody-drug conjugate for the treatment of Hodgkin lymphoma, the first approved treatment for this disease since 1977. The same drug was also approved for anaplastic large-cell lymphoma.

Role of JAK in cancer migration described

Country
United Kingdom

A team of European scientists has described how a member of the Janus kinase (JAK) family of proteins generates contractions in tumours thereby allowing cancer cells to migrate from their site of origin. The findings were published in the journal, Cancer Cell, on 16 August.

Researchers isolate antibodies against HIV

Country
United States

A team of international researchers has isolated 17 new broadly neutralising antibodies that may be effective against many variants of HIV, the virus that causes AIDS. The finding appeared online in Nature on 17 August.

Exon skipping shows promise for Duchenne muscular dystrophy

Country
United Kingdom

An RNA-based therapeutic developed by AVI BioPharma Inc of the US has shown promise as a disease-modifying treatment for patients with Duchenne muscular dystrophy, a fatal genetic disorder, according to an article in The Lancet.

Basilea looks to register antibiotic

Country
Switzerland

Basilea Pharmaceutica Ltd is auditing clinical data for its broad-spectrum cephalosporin antibiotic, ceftobiprole, with a view to making a future regulatory filing. This follows problems with earlier studies conducted by licensee, Johnson & Johnson.

Galápagos extends agreement with Genentech

Country
Netherlands

Galápagos NV has extended for the third time a drug discovery agreement with Genentech (Roche) that involves the use of a number of technologies to discover new chemical entities against targets defined by the Roche group subsidiary.

SkyePharma outlook linked to Flutiform approval

Country
United Kingdom

SkyePharma PC said regulatory clearance in Europe of its asthma drug, Flutiform, is still pivotal to its long-term growth. The company issued the outlook together with the release of its first-half results on 18 August which showed that revenue and operating profit both dropped. This was largely owing to the fact that one-off income the previous year wasn’t repeated.