Cytos Biotechnology Ltd said that it has received the support of bondholders to restructure its outstanding convertible debt with the result that it can continue as a going concern. The refinancing affected CHF 1.225 million of debt.
Since 2003, the European Medicines Agency and the US Food and Drug Administration have been working actively behind the scenes to coordinate decision-making. This doesn’t mean issuing the same opinions on new products. But it does mean sharing intelligence, and taking a common approach to problem-solving.
Researchers from University College London and colleagues have reported the successful administration of a gene therapy to patients with haemophilia B. The study appears in the 10 December New England Journal of Medicine.
A team of European researchers has reported the successful transplantation of a synthetic trachea into a patient with tracheal cancer using a scaffold which was seeded with the patient’s own stem cells.
A decision by the US Food and Drug Administration to allow non-prescription use of an emergency contraceptive for all women of child-bearing age has been overruled by Secretary of Health and Human Services, a political appointee.
Agennix AG, which has a late-stage product for non-small cell lung cancer and severe sepsis in development, has completed a €27.5 million rights issue with participation from existing shareholders. The issue will secure the company’s operations into 2013.
Forbion Capital Partners has raised $50 million for a second co-investment fund whose purpose is to invest in several portfolio companies that are close to an exit. The firm’s first co-investment fund closed in 2010 with commitments of €54 million.
Privately-owned Molecular Partners AG of Switzerland has expanded its relationship with Johnson & Johnson Inc with an agreement to research potential products for a number of immunological diseases using its protein technology.
The UK speciality pharmaceutical group, Sinclair IS Pharma Plc, is to pay £21 million to acquire Advanced Bio-Technologies Inc, giving it full rights outside the US to the topical silicone gel product, Kelo-cote, for scar reduction.
AstraZeneca said it intends to reduce its US sales force by 1,150 or 24% by early February 2012 as part of the company’s ongoing strategy to operate the business more efficiently.