Glide Pharma Ltd has completed a fifth funding round raising £14 million to scale up manufacturing for the production of its solid dose injector system which includes drug product and device. The new round brings funds raised to date to £24.9 million.
Sapiens Steering Brain Stimulation BV of the Netherlands and Germany, has raised €7.5 million from a Dutch investment group in an extension of its Series A financing round. The new funds supplement €16.5 million raised earlier from European and US backers.
A potential $6.6 billion bid for Elan Corp was made 25 February by a private New York investment firm called Royalty Pharma LLC and potentially rejected by Elan’s board of directors.
Merck Serono said that a Phase 3 trial of its integrin inhibitor, cilengitide, for the treatment of glioblastoma did not meet its primary endpoint of significantly increasing overall survival when added to the current standard of care, temozolomide and radiotherapy.
Ablynx NV is to jointly research the potential of its therapeutic proteins conjugated to cytotoxic drugs developed by Spirogen Ltd, in a new research agreement announced by both parties on 25 February. The research collaboration is set to last for up to one year initially with an option to continue.
The US Food and Drug Administration has approved the Roche group’s antibody-drug conjugate, trastuzumab emtansine, for HER2-positive metastatic breast cancer, ushering in a new drug class linking an antibody with a cytotoxic drug.
The European Medicines Agency is recommending approval of a new hexavalent vaccine developed by Sanofi Pasteur that is designed to protect infants against diphtheria, tetanus, pertussis, Hepatitis B, poliomyelitis and Haemophilus influenzae type B (Hib).
H. Lundbeck A/S is set to elect Håkan Björklund, the former chief executive of Nycomed GmbH, as its new chair as the company accelerates efforts to launch new products and increase its pipeline activity. Both revenue and EBIT profit declined in 2012.
The UK-based drug discovery company Domainex Ltd has announced plans to raise £1.5 million in new capital to support its kinase-based drug development programmes for cancer and a variety of inflammatory diseases. The round is being led by Longbow Capital LLP.
UCB SA has signed an agreement with US-based ConfometRX Inc to discover new drugs to treat neurological diseases by targeting the G-protein coupled receptor (GPCR) family of proteins. GPCRs are the largest family of signaling proteins in the human genome.