Real world data from an experimental vaccine for birch pollen allergy, AllerT, have shown statistically significant reductions in seasonal allergy symptoms, as well as an effect into a second pollen season, according to the developer, Anergis SA.
Merck KGaA of Germany has decided to discontinue the clinical development of the immunotherapy tecemotide in non-small cell lung cancer following the failure of a Japanese study to show effectiveness on any trial endpoint.
Eli Lilly and Company said the results of a Phase 3 study of its antibody treatment Cyramza (ramucirumab), which has already been approved for advanced gastric cancer, met its primary endpoint of overall survival in patients with metastatic colorectal cancer.
Data from two Phase 3 studies of the antibody mepolizumab in severe asthma have shown statistically significant reductions in asthma exacerbations and a reduction in the need for daily oral corticosteroid use, according to the developer, GlaxoSmithKline Plc.
Shares of Affimed Therapeutics AG of Germany began trading on the Nasdaq over-the-counter market in the US on 12 September following an initial public offering of eight million new shares. Priced at $7 per share, the shares were trading at $5.98 on 15 September.
AM-Pharma BV of the Netherlands has raised €12.2 million for the further clinical development of its recombinant human alkaline phosphatase product for acute kidney injury and ulcerative colitis – its second major fundraising in three years
Alizé Pharma SAS has raised €5 million to finance further development of an analog of a metabolic hormone that has the potential to treat type-2 diabetes and a rare children’s disease called the Prader-Willi syndrome.
Genmab A/S is expanding its involvement in antibody-drug conjugates (ADCs) with a new agreement to in-license technology from Seattle Genetics Inc. Under the latest deal, the Danish company will develop an ADC for potential use against solid tumours.
The fall-out from an alleged fiddle of Type 1 diabetes research by an Israeli company has spread to California and then on to Germany.
Results of a Phase 2 study of benralizumab from AstraZeneca Plc for chronic obstructive pulmonary disease (COPD) have been published in The Lancet Respiratory Medicine. The drug is said to be the first biologic to show a marked reduction in inflammation.