The cell-therapy company TiGenix NV has raised gross proceeds of $35.65 million in an initial public offering of its shares on the Nasdaq exchange in the US in order to support the clinical development of its allogeneic product portfolio.
Noxxon Pharma AG has become the latest company to reach an agreement with Merck & Co Inc to test a portfolio drug with Keytruda (pembrolizumab), the US company’s immune checkpoint inhibitor.
Negotiations between Johnson & Johnson Inc and Actelion Ltd about a potential transaction have ended without an agreement, the two companies announced. Separately, the Wall Street Journal reported that Sanofi SA is reportedly in talks with Actelion.
UK-based Oxford Nanopore Technologies Ltd has raised £100 million in a private share placement to support the commercial development of its new hand-held device for sequencing whole human genomes at a fraction of the cost of earlier technologies.
The cell-therapy company TiGenix NV has announced plans to make an initial public offering of its shares on the Nasdaq exchange in the US in order to raise money for the clinical development of its portfolio. The company is already listed on Euronext Brussels.
Spark Therapeutics Inc has agreed to make a $10 million cash payment plus an equity investment in Selecta Biosciences Inc for access to a nanoparticle technology that could be used to modulate the immune system and allow repeat dosing of a gene therapy.
Switzerland-based Actelion Ltd and Johnson & Johnson Inc have confirmed that they are in discussions about a “potential transaction.” This is the second negotiation involving Actelion in a little over a year.
Novartis has taken steps to broaden its portfolio of drugs treating haematologic disorders with the acquisition of Selexys Pharmaceuticals Corp of the US which has a product for treating a complication of sickle cell disease that recently completed Phase 2.
CureVac AG, which is developing vaccines based on messenger RNA technology, has raised $29.5 million from two new German investors to advance its portfolio. This follows a private share placement in 2015 that raised $110 million.
Syncona LLP, the evergreen investment fund of the Wellcome Trust, is poised to increase its investment in UK life science through a merger with the Guernsey-based investment fund BACIT Ltd. The new group will keep the Syncona name and be listed on the London Stock Exchange.