Citryll raises funds to target neutrophil traps
Citryll BV, a Dutch biotech, has raised €85 million in a Series B venture capital round to advance a monoclonal antibody drug for two inflammatory diseases by targeting a network of extracellular fibers derived from neutrophils. Neutrophils are the body’s first line of defence against infection. One of their methods of protection is to create neutrophil extracellular traps (NETs), primarily composed of DNA from neutrophils, that can engulf and kill pathogens. But these NETs can also contribute to disease if produced in excess.