Research & University News

Nobel Prize awarded to cell biology pioneers

Two pioneers in cell biology, John Gurdon of the UK and Shinya Yamanaka of Japan, have been awarded the 2012 Nobel Prize in Physiology or Medicine for their work in showing that mature cells can be reprogrammed to become pluripotent.

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Location

Sweden

MRC Technology reports on antibody project

A research project supported by MRC Technology of the UK and directed at new treatments for Alzheimer’s disease, has reached an important threshold with the humanisation of a next-generation antibody binding to amyloid beta.

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Location

United Kingdom

Brain neurons and diet said to influence obesity

New research published in the EMBO Journal suggests that a specific type of neuron in the brain can influence the way the body breaks down and stores nutrients, providing further insight into obesity and other metabolic diseases.

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Location

Germany

MRC to open up its compound library to researchers

Up to 9,000 small-molecule compounds with potential as future drugs are being made available free of charge to academic researchers around the world by MRC Technology, the technology transfer arm of the UK’s Medical Research Council.

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Location

United Kingdom

AZ and Broad Institute to work on infection

AstraZeneca Plc and the Broad Institute in Cambridge, Massachusetts, US have announced a collaboration to identify new chemical compounds targeting bacterial and viral infections. Financial details were not disclosed.

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Location

United Kingdom

Protein’s role in prostate cancer described

UK scientists have reported new findings on the role of heat shock proteins in the development of prostate cancer which suggest that the p23 protein may act independently to activate the androgen hormones that fuel the cancer’s growth.

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Location

United Kingdom

Novartis andUPenn to work on cellular therapies

Novartis has announced plans to invest in a new Center for Advanced Cellular Therapies at the University of Pennsylvania in the US to research immunotherapies for patients with cancer using chimeric antigen receptor (CAR) technologies.

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Location

Switzerland

Meeting Report: Spotlight on advanced therapies

Some 300 clinical trials are underway in Europe testing prospective cell, gene and tissue-engineered therapies. Known as advanced therapy medicinal products (ATMPs), these medicines are being investigated for a broad range of diseases- from macular degeneration to Parkinson’s disease.

 

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Location

Ireland

ThromboGenics, BioInvent give clinical update

Thrombogenics NV and BioInvent International AB have decided to stop development of an early-stage anticoagulant after safety issues were identified. They have also regained a cancer asset from Roche, which has left the programme.

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Location

Belgium

OS data for tasquinimod reported

New data from a Phase 2 study of the prostate cancer drug, tasquinimod, show longer median overall survival times than previously reported for this patient population, according to the sponsors, Active Biotech AB and Ipsen SA. The data were reported at Asco.

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Location

United States

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