Research & University News

Mayo Clinic researchers identify Parkinson's disease gene mutation

Researchers from the Mayo Clinic in the US have reported a new gene mutation linked to Parkinson’s disease and identified in a large Swiss family with the disease. The finding was reported in the American Journal of Human Genetics on 19 July.

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Location

United States

Convergence starts study of drug for pain

A recently created spin-out of GlaxoSmithKline Plc has started a Phase 2 study of a new small-molecule treatment for pain that acts against a sodium channel known as Nav1.7. The company is Convergence Pharmaceuticals Ltd.

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Location

United Kingdom

Roche says combination therapy met primary endpoint

A combination therapy of pertuzumab, trastuzumab and docetaxel for women with HER2-positive metastatic breast cancer has met its primary endpoint of progression-free survival in a Phase 3 study, according to the trial’s sponsor, Roche.

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Location

Switzerland

Evolva reports on drug for diabetic complications

Evolva Holding SA has successfully completed a Phase 1 study of a new small molecule compound that is being positioned to treat people with diabetes at risk of vascular or renal complications. The study involved 32 volunteers.

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Location

Switzerland

EU project to study cell and gene therapy in heart disease

The European Commission has awarded €5.3 million over four years to a consortium led by Ark Therapeutics Group Plc to investigate the possible use of gene and cell therapy, along with stents, in the treatment of coronary heart disease.

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Location

United Kingdom

Ipsen and Salk Institute renew research agreement

Ipsen SA and The Salk Institute for Biological Studies of the US are renewing for another three years, their research collaboration to explore the biology of proliferative and degenerative diseases. Financial details were not disclosed.

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Location

France

SuppreMol to test protein in lupus

Venture-capital backed SuppreMol GmbH has announced the start of a Phase 2a study of a recombinant protein for systemic lupus erythematosus. This follows FDA approval in March of an antibody therapeutic for lupus from GSK, the first new drug for the disease since 1955.

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Location

Germany

Novel antibody against influenza reported

A novel monoclonal antibody that is said to have the potential to neutralise most group 2 influenza A viruses has been described in a paper in the journal Science. The research was conducted by Crucell NV and The Scripps Research Institute of the US.

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Location

Netherlands

Sanofi stops Multaq trial in AF

Sanofi SA has stopped a Phase 3b trial of its antiarrhythmic, Multaq (dronedarone), in patients with permanent atrial fibrillation following a significant increase in cardiovascular events in those receiving the drug.

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Location

France

Study suggests new targeted approach for MS

A study published in Nature Medicine has suggested that inhibiting a receptor called death receptor-6 may represent a novel approach for the treatment of multiple sclerosis. The study was undertaken by researchers at Biogen Idec of the US.

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Location

United States

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