Regenerative Medicine

ESC-derived cells transplanted into the eye

The first embryonic stem-cell derived therapy for the eye has been safely transplanted into two patients with no signs of inflammation, rejection or tumourigenicity, according to a report published online in The Lancet on 24 January 2012.

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Location

United States

Cardio3 BioSciences secures €3.1 million

Cardio3 BioSciences SA has secured €3.1 million in new funding from the Walloon regional government of Belgium and from the European Seventh Framework Programme (FP7) to support development of its stem-cell technology.

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Location

Belgium

ProFibrix reports on US Phase 2 study of sealant

ProFibrix BV of the Netherlands has announced that a Phase 2 US study of its sealant to stop bleeding during and after surgery reached its primary endpoint, confirming the results of an earlier Phase 2 study in the Netherlands.

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Location

Netherlands

Sanofi gets rights to cartilage regeneration programme

Sanofi SA has agreed to pay up to €180 million to privately-held Scil Technology GmbH for exclusive rights to the German company’s preclinical programme for cartilage regeneration. The programme is based on the rhCD-RAP protein.

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Location

Germany

Gene therapy shows benefit in patients with haemophilia B

Researchers from University College London and colleagues have reported the successful administration of a gene therapy to patients with haemophilia B. The study appears in the 10 December New England Journal of Medicine.

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Location

United Kingdom

Transplantation of bioartificial trachea reported

A team of European researchers has reported the successful transplantation of a synthetic trachea into a patient with tracheal cancer using a scaffold which was seeded with the patient’s own stem cells.

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Location

Sweden

UK awards £8.5 million to regenerative medicine projects

Fourteen research and development projects in the field of regenerative medicine are set to receive £8.5 million from the UK government as part of a drive to stimulate innnovation in the sector. The projects will be led by small and medium sized companies.

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Location

United Kingdom

Interim results of cardiac stem cell trial said encouraging

A team of US scientists has reported interim results from a Phase 1 study of an autologous cardiac stem cell therapy which showed a substantial improvement in left ventricular systolic function in patients with heart disease. The findings appear in The Lancet.

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Location

United States

Geron abandons stem cells

Geron Corporation, which launched the first human study of an embryonic stem cell therapy in the west, has decided to leave the stem cell field citing the unfavourable financial environment. It is stopping its trial in patients with spinal cord injury.

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Location

United States

Fibrin sealant meets primary endpoint in Phase 2 trial

A sealant that has been developed to stop bleeding during and after surgery has met its primary endpoint in a Phase 2 trial of patients undergoing liver resection surgery, according to the developer, ProFibrix BV of the Netherlands.

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Location

Netherlands

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